Tooth decay is a tissue dependent process of varying etiology polymicrobial diseases including dental caries are not infectious for decades the sugar fermenting acidogenic species streptococcus mutans has been considered the main causative agent of dental caries and most diagnostic and therapeutic strategies have been targeted toward this . Etiology of dental caries 1 etiology of dental caries introduction definition dental caries is a microbial disease of the calcified tissues of the teeth characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth it is the most prevalent chronic disease affecting the human race. Studies of the pathology of enamel of human teeth with special reference to the etiology of caries. Solving the etiology of dental caries recent dna and rna based studies from carious lesions have uncovered an extraordinarily diverse ecosystem where s mutans accounts only a tiny fraction . This monograph on dental caries is based on the special pathology of the tissues concerned the author rightly states a correct knowledge and understanding of normal structures is a fundamental requirement for the study of their pathological changes
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